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Cialis

Known as the “week-end pill”, due to its long lasting effect – up to 36 hours – Cialis is another drug to treat erectile dysfunction. With tadalafil as its active ingredient effects are seen within 30 minutes. The administration for this drug comes in two dosages of 10 mg and 20 mg

Author

Adam Miller – pharmacist

Author

Adam Miller – pharmacist

What are the benefits of the treatment with Cialis?

Men who are taking Cialis first of all enjoy its long lasting effect which is up to 36 hours. That means much longer than Viagra and Levitra together. This long period of effectiveness gives you flexibility for your plans, allowing you at the same time to fully enjoy a normal and unplanned sexual life. And you don`t have to worry about unpleasant effects. Another great asset of this pill is the fact it has the quickest reaction time (20-30 minutes), better than Viagra or Levitra.

How does Cialis work?

Again, in order to understand how an erectile dysfunction treatment works, you will have to understand the body mechanisms that lie behind an erection. When aroused, nitric oxide (NO) is released by the nervous system located inside the erectile tissue of the penis. The nitric oxide stimulates cyclic guanosine monophosphate (cGMP). This enzyme is responsible for loosen up the smooth muscle cells, which will make your arteries dilated in order to increase the blood flow to the penile tissues. As a result of this process you will obtain an erection. On the contrary, an erection will not be possible when the level of PDE-5 is too high. This will restrict the blood flow and your penis will stay emasculated even when you are sexual stimulated. Basically the active ingredient, tadalafil, of Cialis prevents this situation, by keeping in the control the PDE-5. In order for Cialis to work, you will of course need sexual stimulation. 

Who can use the Cialis treatment?

If you are over 18 years old and you`re diagnosed with erectile dysfunction on regular basis, Cialis can be the proper way of treating it. This medicine is especially recommended to those men with a constant relationship and who therefore enjoy a constant sexual activity. The presence of the chemical messengers responsible for the erection and sexual stimulation are in order. 

Just like any other impotence drug, the right dosage must be established taking into consideration your medical status or if you are at the beginning of your treatment and you`re thinking taking Cialis for the first time. Most doctors recommend a low dosage at the beginning of the treatment, increasing it if necessary. Acting this way, any side effects and unnecessary risk are avoided. 

 

Who shouldn`t take Cialis?

Since Cialis is known in the medical world to lower the blood pressure, you are not suitable for this drug if you have a blood pressure condition or if you have been currently prescribed with any nitrate medication. 

  • If you have a medical condition who fits into any of the following disorders, Cialis might not be the proper erectile dysfunction treatment for you: 
  • If you had a stroke or a heart attack and you are in the recovering process.
  • If you were diagnosed with rare hereditary problems related to galactose intolerance, glucose-galactose malabsorption or lapp lactase deficiency.
  • If you`re suffering from a serious heart disorder, unstable angina or severe heart failure included.
  • If you were diagnosed with retinis pigmentosa, a hereditary degeneration regarding the back part of the eyeball.

Likewise, if you have a history of diabetes or high cholesterol, you better try Levitra as treatment for your erectile dysfunction. Keep in mind stating your medical history in the online consultation is extremely important. A good medical decision comes when the doctor has the full picture. This is the best way avoiding unnecessary risk and getting the wanted result.

Dosages

Cialis is available in doses of 10mg and 20mg. Never try to exceed the 20mg dosage or you will expand the risk for side effects. 

The ideal patients for the 20mg dosage of this dug are healthy men. Yet, in order to bypass unwanted side effects, a 10mg dosage is most suitable at the beginning. 

No matter the dosage prescribed, Cialis will stay active in the body for 36 hours. Remember to list any current medications in the online consultation. 

10mg Dosage
Doctors will prescribe this dosage in case of kidney or liver disorder, if you`re taking any medicine for high blood pressure (alpha-blockers for instance) or if you have a history in experiencing side effects when taking other drugs. 

With this dosage the risk of any side effects is minimized and the effectiveness is very high. Most men will solve their erectile dysfunction whit only 10mg. 

20mg dosage
If you are a healthy men, with no historical medical record, then, most probably the doctor will prescribe you 20mg dosage of Cialis. Even if you have never taken Cialis, but you have a healthy status, chances are you will start the treatment with this dosage. Practice has shown some very severe cases of erectile dysfunction treated with this dosage of Cialis. Even so, don`t make the mistake of taking more than one tablet in a period of 36 hours. This is dangerous and no doctor will ever recommend this.

How do I take Cialis?

Cialis must be administrated at least 30 minutes before sexual intercourse. But the great thing when taking Cialis is that you can take the pill much sooner and still enjoy its effects, since it stays in the body up to 36 hours. 

The starting dose is 10mg. If the erection fails to appear and you haven`t experienced side effects, it is possible for a higher dose to be recommended. 

Also, keep in mind Cialis interacts with grapefruit juice. It is advisable avoiding this drink when taking Cialis, because it has a chemical which will increase the level of tadalafil in the bloodstream, and the side effects will tend to have a higher incidence. Also, abstaining drinking alcohol is a must, unless you want to experience dizziness, as a result of low blood pressure. More to this, alcohol is known to affect the sexual performance. 

Some daily activities may be affected by this drug. Special attention is needed when driving or handling machinery. A full evaluation of how your body reacts to this drug is needed, in order to stay safe. For optimal information or if you have any doubts do not hesitate to contact your prescriber. 

What are the side effects when taking Cialis?

Although side effects rarely occur, there is always a small possibility for them to show. Among Cialis side effects, most reported were headache, indigestion and facial flushing. Normally, they should last for short periods of time. In case they persist please contact your doctor. He will either lower the dose of Cialis or go for another impotence treatment, more suitable for you. 

What is the story of Cialis?

First steps for the Cialis drug was taken in 1993, when the Icos pharmaceutical company started to research IC351, a PDE5 enzyme inhibitor. Interesting fact, one year later Pfizer identified the fact that sildenafil citrate can be used in erectile dysfunction. Rumor has it, just like in Pfizer case, the Icos researchers had no clue IC351 can be used in erectile problems; this came as a later discovery. So, it`s unclear if the patent on IC351, which was obtained in 1994, was released before or after Pfizer conclusion regarding sildenafil. Clinical trials performed by Icos continued over several years. The testing clinical phase lasted up to two years. In 1998, after a new demand of the Icos company to the U.S. Food and Drug Administration regarding IC351, the treatment was renamed Cialis. The approval of the treatment was released in 2003, when Icos and Lilly (these two companies merged their forces in 1998) managed to prove the fact Cialis stays in the body up to 36 hours, which clearly differentiate Cialis from Viagra.

Cialis History

Cialis History

What is the story of Cialis?

First steps for the Cialis drug was taken in 1993, when the Icos pharmaceutical company started to research IC351, a PDE5 enzyme inhibitor. Interesting fact, one year later Pfizer identified the fact that sildenafil citrate can be used in erectile dysfunction. Rumor has it, just like in Pfizer case, the Icos researchers had no clue IC351 can be used in erectile problems; this came as a later discovery. So, it`s unclear if the patent on IC351, which was obtained in 1994, was released before or after Pfizer conclusion regarding sildenafil. Clinical trials performed by Icos continued over several years. The testing clinical phase lasted up to two years. In 1998, after a new demand of the Icos company to the U.S. Food and Drug Administration regarding IC351, the treatment was renamed Cialis. The approval of the treatment was released in 2003, when Icos and Lilly (these two companies merged their forces in 1998) managed to prove the fact Cialis stays in the body up to 36 hours, which clearly differentiate Cialis from Viagra.

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